Arrhythmias & electrophysiologyCohort study

Early recurrence of atrial arrhythmias and its impact on late recurrence after pulmonary vein isolation using pulsed field ablation of paroxysmal atrial fibrillation: A long-term follow-up study

Heart RhythmPublished

  • single-center, prospective study
  • consecutive patients

Authors' conclusion

Early AF/AFL/AT recurrence was a significant risk factor for late atrial arrhythmia recurrence after single-shot PVI-PFA. Although a significant portion of the participants experienced atrial arrhythmia recurrence, the overall arrhythmia burden in this subgroup remained low.

Study context

Population
Consecutive patients aged >18 years undergoing single-shot pulsed field ablation (PFA) for symptomatic paroxysmal atrial fibrillation (AF), with concomitant PVI-PFA and implantable loop recorder (ILR) implantation
Participants
52 patients

Main finding

As reported in the abstract

AF/AFL/AT recurrence during the observation period · median follow-up 24 months

Patients with AF/AFL/AT recurrence

34 (65%)

Observational data: associations, not effects.

Further findings

Early recurrence of atrial arrhythmias

Patients with early recurrence
20 patients (38%)
Of those with early recurrence, all experienced late recurrence as well

Arrhythmia burden

Overall arrhythmia burden in the entire cohort
0.01%
Median arrhythmia burden among patients with recurrence
0.3%

Follow-up

Median follow-up period
24 months
interquartile range; min-max
14-30; 12-36

Original publication

Early recurrence of atrial arrhythmias and its impact on late recurrence after pulmonary vein isolation using pulsed field ablation of paroxysmal atrial fibrillation: A long-term follow-up study. Heart Rhythm. Published 4 March 2026. doi:10.1016/j.hrthm.2026.02.047

Summarised from the published abstract; every number is checked against it