Coronary disease & ACSRandomised controlled trial
Early vs Late Staged Percutaneous Coronary Intervention (PCI) After Subintimal Tracking and Re-Entry for Chronic Total Occlusions
- Randomised controlled trial
- multicentre (6 centres)
Authors' conclusion
Although vessel patency was higher at the start of early staged procedures, there were no statistically significant differences for partial technical success of the staged procedure with early or late treatment.
Study context
- Population
- Patients undergoing chronic total occlusion (CTO) PCI with subintimal tracking and re-entry (STAR) and deferred stenting
- Participants
- 150 patients
- Comparison
- Early vs late staged PCI after STAR
- Earlyn = 73
- Laten = 77reference
- Primary endpoint
- Partial technical success of the staged procedure (TIMI flow grade 2-3 with <30% residual stenosis into at least 1 ≥2.5 mm distal branch)
Primary result
As reported in the abstract
P = 0.08
Further findings
TIMI flow grade 2-3 in target vessel at start of staged procedure · P = 0.048 after adjustment
P = 0.012
Original publication
Early vs Late Staged PCI After Subintimal Tracking and Re-Entry for Chronic Total Occlusions. J Am Coll Cardiol. Published 26 November 2025. doi:10.1016/j.jacc.2025.09.1598
Summarised from the published abstract; every number is checked against it