Heart failure & cardiomyopathiesRandomised controlled trial
Echocardiographic screening for heart failure and optimization of the care pathway for individuals with pacemakers: a randomized controlled trial
- Randomised controlled trial
- multicentre
Authors' conclusion
The results of this trial indicate that echocardiography screening commonly identifies LVSD in individuals with pacemakers but alone does not alter outcomes.
Study context
- Population
- Patients with a pacemaker717 men
- Participants
- 1,201 patients
- Comparison
- Echocardiography screening vs usual care
- Echocardiography screeningn = 600
- Usual caren = 601reference
- Primary endpoint
- Composite of:
- Time to first HF hospitalization
- Death
Primary result
As reported in the abstract
31 months (IQR 30-40 months)
Hazard ratio
0.89
95% CI 0.69–1.17
Events by treatment group
Echocardiography screening vs Usual care
HR 0.89 (95% CI 0.69–1.17)
Further findings
| Outcome | Echocardiography screening | Usual care |
|---|---|---|
| LVSD detected (screening arm) | 34% | Not reported in the abstract |
Primary outcome in left ventricular systolic dysfunction (LVSD), specialist clinic vs primary care (subgroup)
- Primary outcome event less frequent with specialist clinic management than with primary care
- prespecified, nonrandomized, exploratory analysis
Original publication
Echocardiographic screening for heart failure and optimization of the care pathway for individuals with pacemakers: a randomized controlled trial. Nat Med. Published 19 September 2024. doi:10.1038/s41591-024-03265-3
Summarised from the published abstract; every number is checked against it