Arrhythmias & electrophysiologyRandomised controlled trial
Education of healthcare professionals to improve guideline adherence in atrial fibrillation: the STEEER-AF cluster-randomized clinical trial
- Cluster randomised controlled trial
- 70 centres in six countries
Authors' conclusion
Thus, while the education of healthcare professionals improved substantial gaps in implementation for rhythm control, it had no significant effect on stroke prevention.
Study context
- Population
- Patients with atrial fibrillation (AF) seen in routine practice
- Participants
- 1,732 patients · 70 centres
- Comparison
- Education of healthcare professionals vs standard practice
- Primary endpoint
- Co-primary: guideline adherence (ESC class I and III recommendations) on stroke prevention and on rhythm control
- Follow-up
- 6-9-months follow-up
Primary result
As reported in the abstract
Guideline adherence
Intervention
67.5%
Stroke prevention · Rhythm control 33.9%
Control
60.9%
Stroke prevention · Rhythm control 22.9%
Intervention vs ControlAdjusted relative risk (95% CI)P value
stroke prevention
1.10(0.97–1.24)
P = 0.13rhythm control
1.51(1.04–2.18)
P = 0.03Secondary outcomes
| Outcome | improvement (%) (95% CI) | P value |
|---|---|---|
| Patient-reported integrated AF management | 5.1 (1.4%–8.9%) | P = 0.01 |
Original publication
Education of healthcare professionals to improve guideline adherence in atrial fibrillation: the STEEER-AF cluster-randomized clinical trial. Nat Med. Published 13 June 2025. doi:10.1038/s41591-025-03751-2
Summarised from the published abstract; every number is checked against it