Coronary disease & ACSSecondary analysis
Effect of age on restrictive and liberal transfusion outcomes in patients with anemia and myocardial infarction
- prespecified MINT substudy
Authors' conclusion
A liberal transfusion approach appears to be safe and may be the preferred transfusion strategy in anemic patients with MI, regardless of age.
Study context
- Population
- Patients with anemia and myocardial infarction (MI), younger and olderpatients in the randomized MINT trial
- Participants
- 3,504 patients
- Comparison
- liberal versus restrictive transfusion in younger and older patients
Primary result
As reported in the abstract
Interaction between age and transfusion strategy for death or MI, heart failure, revascularization procedures, cardiac death, pulmonary embolism or deep vein thrombosis, bacteremia or pneumonia, and death · 30 and 180 days
- no significant interaction between age and transfusion strategy
Original publication
Effect of age on restrictive and liberal transfusion outcomes in patients with anemia and myocardial infarction. Am Heart J. Published 19 February 2026. doi:10.1016/j.ahj.2026.107381
Summarised from the published abstract; every number is checked against it