Arrhythmias & electrophysiology
Effect of telemedicine-based integrated management of atrial fibrillation in village clinics on recurrent nonfatal cardiovascular events: a secondary analysis of the MIRACLE-AF trial
Primary result · Recurrent nonfatal events (strokes, hospitalizations for worsening heart failure or acute coronary syndrome, and emergency visits for AF)Result — go to the resultHazard ratio 0.76 95% CI 0.583–1.004Authors' conclusion
Although the overall difference did not reach statistical significance, directional trends consistently favored telemedicine-based integrated care, suggesting a potential reduction in recurrent cardiovascular event burden. Larger studies with longer follow-up are needed to confirm these findings.
Study context
- Population
- Rural patients aged ≥65 years with confirmed atrial fibrillation (AF)rural patients across 30 village clinics
- Participants
- 1,039 patients
- Comparison
- Village doctor-led telemedicine integrated care or enhanced usual care
- Primary endpoint
- Recurrent nonfatal events:
- Strokes
- Hospitalizations for worsening heart failure or acute coronary syndrome
- Emergency visits for AF
- Follow-up
- 36 months
Methodological detailscluster-randomized controlled trial, 30 village clinics, village clinics randomized 1:1, conditional frailty model
- Cluster-randomized controlled trial
- 30 village clinics
- Village clinics randomized 1:1
- Conditional frailty model
Primary result
As reported in the abstract
Hazard ratio
0.76
95% CI 0.583–1.004
P = 0.053
Events by treatment group
Interventionvs control
hazard ratio 0.76 (95% CI 0.583–1.004); P = 0.053
Original publication
Effect of telemedicine-based integrated management of atrial fibrillation in village clinics on recurrent nonfatal cardiovascular events: a secondary analysis of the MIRACLE-AF trial. Heart Rhythm. Published 22 October 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →