Cardiometabolic & kidneySecondary analysis
Effects of an Intervention to Improve Evidence-Based Care for People With Diabetes and Cardiovascular Disease Across Sex, Race, and Ethnicity Subgroups: Insights From the COORDINATE-Diabetes Trial
- Secondary analysis of the COORDINATE-Diabetes randomised trial
- cluster randomised
- prespecified analysis
- 43 US cardiology clinics
Authors' conclusion
The COORDINATE-Diabetes intervention successfully improved delivery of evidence-based care, regardless of sex, race, or ethnicity.
Study context
- Population
- Participants with T2DM and atherosclerotic CVD at US cardiology clinics
- Participants
- 1,045 participants
- Comparison
- Intervention vs Usual care
- Primary endpoint
- Proportion prescribed all 3 groups of evidence-based therapy (high-intensity statin, ACEi/ARB, and SGLT2 inhibitor or GLP-1 receptor agonist)
- Follow-up
- Last trial assessment (6 to 12 months)
Primary result
As reported in the abstract
Prescribed all 3 evidence-based therapy groups, by subgroup · last trial assessment
Consistent benefit across sex (male vs female)
Pinteraction=0.44
Consistent benefit across race (Black vs White)
Pinteraction=0.59
Consistent benefit across ethnicity (Hispanic vs Non-Hispanic)
Pinteraction= 0.78
Original publication
Effects of an Intervention to Improve Evidence-Based Care for People With Diabetes and Cardiovascular Disease Across Sex, Race, and Ethnicity Subgroups: Insights From the COORDINATE-Diabetes Trial. Circulation. Published 27 June 2024. doi:10.1161/circulationaha.124.068962
Summarised from the published abstract; every number is checked against it