Heart failure & cardiomyopathiesMeta-analysis
Effects of detraining on left ventricular mass in endurance-trained individuals: a systematic review and meta-analysis
- Systematic review and meta-analysis of prospective detraining studies
- random effects
- meta-regression
Authors' conclusion
In summary, LVM is reduced following detraining of one week or more.
Study context
- Population
- Endurance-trained healthy adults without known chronic disease (ages 18–55 years, 15% female), detraining >1 week19 analyses
- Participants
- 196 adults · 15 studies
- Comparison
- Post-detraining vs pre-detraining left ventricular mass (LVM)
- Outcome
- Change in LVM with detraining
- Follow-up
- Detraining 1.4 to 15 weeks
Pooled result
As reported in the abstract
Standardized mean difference
−0.586
95% CI −0.817 to −0.355
P < 0.001
Post-detraining vs pre-detraining LVM
standardized mean difference −0.586 (95% CI −0.817 to −0.355); P < 0.001
Further pooled results
Length of detraining and change in LVM
- Meta-regression: length of detraining, accounting for training status, associated with LVM reduction
- Q = 15.20, df = 3, P = 0.0017
- Length of detraining alone not correlated with change in LVM
LVM reduction by training status
- Greater LVM reduction in highly trained/elite athletes vs recreational and newly trained individuals
- P < 0.01
Original publication
Effects of detraining on left ventricular mass in endurance-trained individuals: a systematic review and meta-analysis. Eur J Prev Cardiol. Published 11 October 2023. doi:10.1093/eurjpc/zwad327
Summarised from the published abstract; every number is checked against it