Arrhythmias & electrophysiologyResearch article

Effects of Pulsed Field Ablation for Pulmonary Vein Isolation on Vein of Marshall Electrograms

JACC Clin ElectrophysiolPublished

  • Not stated
  • continuous vein of Marshall (VoM) electrogram recording with a 1.6-F electrode catheter

Authors' conclusion

The impact of PFA on VoM electrograms varied among PFA systems and was largely determined by the PFA electrode-VoM distance. Notably, the majority of VoM electrogram alterations were transient.

Study context

Population
Patients undergoing pulsed field ablation (PFA)-based PV isolationpatients undergoing PFA-based PV isolation · FARAPULSE 28 · VARIPULSE 21 · PulseSelect 23
Participants
72 patients
Comparison
FARAPULSE vs VARIPULSE vs PulseSelect
  • FARAPULSEn = 28
  • VARIPULSEn = 21
  • PulseSelectn = 23

Main finding

As reported in the abstract

VoM electrogram effect during PFA-based PV isolation

VoM electrograms eliminated

16 patients (22%)

VoM electrograms reduced

16 patients (22%)

Further findings

PFA electrode-VoM distance by electrogram effect (median [Q1-Q3])

  • PFA electrode-VoM distance by electrogram effect (median [Q1-Q3]): P < 0.001

Extent of VoM electrogram alteration by PFA system

Differed among PFA systems and was greatest with FARAPULSE
P < 0.001

Recovery among patients with acute VoM electrogram elimination · by the end of the procedure

Persistent elimination, among patients with acute VoM electrogram elimination
9 patients (56%)
Partial recovery, among patients with acute VoM electrogram elimination
1 patient (6%)
Complete restoration, among patients with acute VoM electrogram elimination
6 patients (38%)

Recovery among patients with acute VoM electrogram reduction

All patients with acute VoM electrogram reduction showed complete recovery

Persistent VoM electrogram modification

Overall, of patients undergoing PFA-based PV isolation
14%

Original publication

Effects of Pulsed Field Ablation for Pulmonary Vein Isolation on Vein of Marshall Electrograms. JACC Clin Electrophysiol. Published 22 July 2026. doi:10.1016/j.jacep.2026.06.015

Summarised from the published abstract; every number is checked against it