Pulmonary vascular disease & thromboembolism
Efficacy and safety of catheter-based thrombectomy versus catheter-directed thrombolysis in acute pulmonary embolism
Authors' conclusion
When compared with performance goal for CDT based on historical studies, CBT was noninferior for all-cause mortality (6.0% vs 6.87%; P-valueNI < .001), non-inferior and superior for major bleeding (4.9% vs 11%; P-valueNI < .001 and P < .001 for superiority).
Study context
- Population
- Acute PE
- Comparison
- Catheter-based thrombectomy (CBT) vs performance goal for catheter-directed thrombolysis (CDT)
- Outcome
- All-cause mortality
Methodological detailscomparison with performance goal rates from a published network meta-analysis, non-inferiority
- Comparison with performance goal rates from a published network meta-analysis
- Non-inferiority
Pooled result
As reported in the abstract
P-valueNI < .001
Safety
Major bleeding · non-inferior
P-valueNI < .001
| Outcome | P value |
|---|---|
| Major bleedingSuperior | P < 0.001 |
Original publication
Efficacy and safety of catheter-based thrombectomy versus catheter-directed thrombolysis in acute pulmonary embolism. Am Heart J. Published 17 April 2024. doi:10. 1016/ j. ahj. 2024. 03. 009
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