Arrhythmias & electrophysiologyCohort study
Efficacy and safety of focal pulsed-field ablation for ventricular arrhythmias: two-centre experience
- Prospective observational study
- two-centre
Authors' conclusion
Pulsed electric field catheter ablation of a broad spectrum of VA is feasible with acute high efficacy; however, the short-term follow-up is less satisfactory for patients with scar-related VT.
Study context
- Population
- Patients with frequent ventricular premature complexes (VPCs) (48%) or scar-related ventricular tachycardia (VT) (52%) undergoing focal pulsed-field catheter ablation
- Participants
- 44 patients
- Exposure
- VPC vs VT
Main finding
As reported in the abstract
Acute success (elimination of VPC or non-inducibility of VT)
- Acute success, all patients
- 84%
Observational data: associations, not effects.
Further findings
| Outcome | VPC | VT |
|---|---|---|
| Freedom from any VA · mean follow-up 116 ± 75 days | Not reported in the abstract | 52% |
Safety
Transient conduction system block during PF applications
- Transient conduction system block (current leakage from proximal shaft electrodes)
- 3 (7%)
Original publication
Efficacy and safety of focal pulsed-field ablation for ventricular arrhythmias: two-centre experience. Europace. Published 11 July 2024. doi:10.1093/europace/euae192
Summarised from the published abstract; every number is checked against it