Arrhythmias & electrophysiologyCohort study
Electrical storm treatment by percutaneous stellate ganglion block: the STAR study
- Prospective multicentre observational study
- single-arm
Authors' conclusion
The findings of this large, prospective, multicentre study provide evidence in favour of the effectiveness and safety of PSGB for the treatment of refractory ES.
Study context
- Population
- Patients with electrical storm refractory to standard treatment, 19 centres, 1 July 2017 to 30 June 2023
- Participants
- 131 patients · 184 percutaneous stellate ganglion block (PSGBs)
- Exposure
- 12 h after vs 12 h before percutaneous stellate ganglion block
- PSGBn = 131
- Outcome
- Reduction of treated arrhythmic events by ≥50%, 12 h after vs 12 h before PSGB
- Follow-up
- 12 h
Main finding
As reported in the abstract
Reduction of treated arrhythmic events by ≥50%
| Group | Value | Median reduction of arrhythmic episodes |
|---|---|---|
| PSGB | 92% | 100% (IQR −100% to −92.3%) |
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Treated arrhythmic episodes, 12 h before first vs 12 h after last PSGB · six (3-15.8) vs. 0 (0-1) | P < 0.0001 |
| Treated arrhythmic episodes, 1 h before vs 1 h after each PSGB · 2 (0-6) vs. 0 (0-0) | P < 0.001 |
Safety
Major complication
- One major complication
- 0.5%
Original publication
Electrical storm treatment by percutaneous stellate ganglion block: the STAR study. Eur Heart J. Published 30 January 2024. doi:10.1093/eurheartj/ehae021
Summarised from the published abstract; every number is checked against it