Arrhythmias & electrophysiologyResearch article
Electrographic flow mapping of persistent atrial fibrillation: intra- and inter-procedure reproducibility in the absence of ‘ground truth’
- Reproducibility study
Authors' conclusion
Electrographic flow mapping generates reproducible intra- and inter-procedural maps, providing rationale for randomized clinical trials targeting these putative AF sources.
Study context
- Population
- Persistent atrial fibrillation (AF) patients after pulmonary vein isolation (PVI), electrographic flow (EGF) mapping with 64-electrode basket catheter12 returned for 3-month remapping
- Participants
- 23 patients
- Outcome
- Intra- (3 min) and inter- (>3 months) procedure EGF map reproducibility
Main finding
As reported in the abstract
Intra-procedure reproducibility (224 map triplets: 111 right atrium, 113 left atrium) · 3 min
Exact match of leading sources on all 3 maps
97 triplets (43%)
Leading source within 1 electrode space on 2 of 3 maps
95 triplets (42%)
Chaotic leading source pattern
32 triplets (14%)
Average deviation in source prevalence over 60 s
6.4%
Further findings
Inter-procedure reproducibility (spatiotemporal stability of EGF mapping) · >3 months
- Stable sources, of sources mapped in 12 patients with (re)inducible AF
- 16 of 18 (89%)
- 1 patient non-inducible at remapping
Original publication
Electrographic flow mapping of persistent atrial fibrillation: intra- and inter-procedure reproducibility in the absence of ‘ground truth’. Europace. Published 10 November 2023. doi:10.1093/europace/euad308
Summarised from the published abstract; every number is checked against it