HypertensionCohort study
Electronic Cigarette Use and Risk of Hypertension
- population-based cohort study
- 4 U.S. communities
- complex survey design
Authors' conclusion
Ever e-cigarette use was associated with increased risk of incident hypertension, suggesting potential long-term cardiovascular harm.
Study context
- Population
- Individuals aged 18 to 74 years in the HCHS/SOL (Hispanic Community Health Study/Study of Latinos)participants with e-cigarette data, cohort includes 11,623 individuals
- Participants
- 11,593 individuals
- Exposure
- Ever vs never e-cigarette use
- ever e-cigarette usen = 937
- current usen = 136
Main finding
As reported in the abstract
Prevalent hypertension
- Ever vs never e-cigarette use was not associated with prevalent hypertension
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Incident hypertension · median follow-up of 6.0 years — ever e-cigarette use vs never use | 1.49 (1.14–1.95) | |
| Incident hypertension · median follow-up of 6.0 years — current use vs never use | 1.89 (1.12–3.18) | |
| Incident hypertension · median follow-up of 6.0 years — former use vs never use | 1.43 (1.07–1.93) | |
| Incident hypertension · median follow-up of 6.0 years — dual ever use vs never use | 1.85 (1.37–2.49) | |
| 0.20.5125Hazard ratio (log scale) |
- Incident hypertension — participants developed hypertension
- 1,409
Longitudinal blood pressure (BP) change from visit 2 to 3
- Longitudinal BP change did not differ by e-cigarette use
Original publication
Electronic Cigarette Use and Risk of Hypertension. JACC Adv. Published 14 January 2026. doi:10.1016/j.jacadv.2025.102525
Summarised from the published abstract; every number is checked against it