Hypertension

Electronic Cigarette Use and Risk of Hypertension: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

JACC AdvPublished population-based cohort study

Authors' conclusion

Ever e-cigarette use was associated with increased risk of incident hypertension, suggesting potential long-term cardiovascular harm.

Study context

Population
Individuals aged 18 to 74 years in the HCHS/SOL (Hispanic Community Health Study/Study of Latinos)participants with e-cigarette data, cohort includes 11,623 individuals
Participants
11,593 individuals
Exposure
Ever vs never e-cigarette use
  • Ever e-cigarette usen = 937
  • Current usen = 136
Outcome
Prevalent hypertension
Methodological details4 U.S. communities, complex survey design
  • 4 U.S. communities
  • Complex survey design

Main finding

As reported in the abstract

  • Ever vs never e-cigarette use was not associated with prevalent hypertension

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)
Incident hypertension · median follow-up of 6.0 yearsEver e-cigarette usevs never use1.49 (1.14–1.95)
Incident hypertension · median follow-up of 6.0 yearsCurrent usevs never use1.89 (1.12–3.18)
Incident hypertension · median follow-up of 6.0 yearsFormer usevs never use1.43 (1.07–1.93)
Incident hypertension · median follow-up of 6.0 yearsDual ever usevs never use1.85 (1.37–2.49)
Incident hypertension — participants developed hypertension
1,409

Longitudinal blood pressure (BP) change from visit 2 to 3

Longitudinal BP change did not differ by e-cigarette use

Original publication

Electronic Cigarette Use and Risk of Hypertension: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL). JACC Adv. Published 14 January 2026. doi:10.1016/j.jacadv.2025.102525

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