Valvular & structural heart diseaseCohort study
Eligibility for Transcatheter Tricuspid Valve Interventions in Patients With Tricuspid Regurgitation
- Retrospective cohort study
- consecutive patients
Authors' conclusion
Of 491 patients requiring TTVI, 32.0% had unfavorable anatomy for T-TEER, and 37.3% of patients with CCT images were eligible for TTVR. Despite the emergence of TTVR devices, 23.2% of patients with TR remained ineligible for both T-TEER and TTVR.
Study context
- Population
- Consecutive patients with tricuspid regurgitation (TR) considered for transcatheter tricuspid valve intervention in heart team conferences327 with cardiac computed tomographic (CCT) images
- Participants
- 491 patients
- Exposure
- Favorable vs Feasible vs Unfavorable
- Favorablen = 99
- Feasiblen = 235
- Unfavorablen = 157
- Outcome
- Prevalence of eligibility for T-TEER and TTVR devices
Main finding
As reported in the abstract
Anatomical feasibility for T-TEER
- Ineligible for transcatheter tricuspid valve replacement (TTVR) (of 327 with CCT images)
- 205 (62.7%)
- Ineligible for both tricuspid transcatheter edge-to-edge repair (T-TEER) and TTVR
- 23.2%
Observational data: associations, not effects.
Further findings
Reasons for unfavorable T-TEER anatomy
- Large coaptation gap width
- 66.2%
- Anteroposterior TR jet location
- 62.4%
Main reason for TTVR ineligibility
- Tricuspid annuli larger than commercially available prosthesis sizes
- 65.4%
Original publication
Eligibility for Transcatheter Tricuspid Valve Interventions in Patients With Tricuspid Regurgitation. JACC Cardiovasc Interv. Published 9 December 2024. doi:10.1016/j.jcin.2024.09.019
Summarised from the published abstract; every number is checked against it