HypertensionRandomised controlled trial

Emergency Department–Based Education and mHealth Empowerment Intervention for Hypertension

JAMA CardiolPublished

  • Randomised controlled trial
  • single-centre

Authors' conclusion

In this single-center randomized clinical trial, a multicomponent intervention directed at patients in the ED who have elevated BP was associated with greater reduction in SBP at 6 months.

Study context

Population
Patients with elevated BP (≥140/90 and ≤180/110 mm Hg) discharged from an urban academic medical centre emergency department (ED)413 with 6-month BP data
Participants
574 patients
Comparison
E2 intervention vs usual care
  • E2n = 210
  • Usual caren = 203reference
Primary endpoint
Mean change in systolic blood pressure (SBP) from baseline
Follow-up
6 months

Primary result

Mean change in SBP

Mean difference

4.9 mm Hg

95% CI 0.8–9.0

P = 0.02

E2 vs Usual care
mean difference 4.9 mm Hg (95% CI 0.8–9.0); P = 0.02

As reported in the abstract

Further findings

OutcomeP value
BP ≤140/90 mm Hg · 6 months · similar proportionP = 0.22
BP ≤140/90 mm Hg — Intervention arm (90 of 210)
42.9%
BP ≤140/90 mm Hg — Control arm (75 of 203)
36.9%

Original publication

Emergency Department–Based Education and mHealth Empowerment Intervention for Hypertension. JAMA Cardiol. Published 1 July 2025. doi:10.1001/jamacardio.2025.0675

Summarised from the published abstract; every number is checked against it