Valvular & structural heart diseaseCohort study
Employment of Artificial Intelligence for an Unbiased Evaluation Regarding the Recovery of Right Ventricular Function after Mitral Valve Transcatheter Edge-to-Edge Repair
- Registry study
- dual-centre
Authors' conclusion
While M-TEER improves left-sided haemodynamics, it does not lead to significant RV function recovery, as confirmed by both conventional echocardiography and artificial intelligence.
Study context
- Population
- Patients undergoing M-TEER for severe mitral regurgitation (MR)
- Participants
- 851 patients
- Exposure
- Baseline vs 3-month follow-up after M-TEER
- Outcome
- Change in right ventricular (RV) function (TAPSE and deep learning–predicted RVEF from apical four-chamber echo videos)
- Follow-up
- baseline to 3-month follow-up
Main finding
As reported in the abstract
Tricuspid annular plane systolic excursion (TAPSE), median: from 17 mm [IQR 14-21 mm] to 18 mm [IQR 15-21 mm]
p = 0.603
Predicted RV ejection fraction (RVEF), median: from 43.1% [IQR 39.1-47.4%] to 43.2% [IQR 39.2-47.2%]
p = 0.475
Observational data: associations, not effects.
Further findings
Left atrial (LA) volume · baseline to 3-month follow-up
- Median LA volume from 123 ml (IQR 92-169 ml) to 104 ml (IQR 78-142 ml); significant reduction after M-TEER
- P < 0.001
Estimated systolic pulmonary artery pressure (sPAP) · baseline to 3-month follow-up
- Median sPAP from 46 mmHg (IQR 35-58 mmHg) to 41 mmHg (IQR 32-54 mmHg); significant reduction after M-TEER
- P = 0.036
1-year survival
- 1-year survival rate
- 86.8%
Original publication
Summarised from the published abstract; every number is checked against it