Heart failure & cardiomyopathies
Enhancing Sweat Rate Using a Novel Device for the Treatment of Congestion in Heart Failure
Authors' conclusion
Enhancing sweat rate was safe and resulted in a clinically meaningful fluid removal and weight loss.
Study context
- Population
- HF patients with congestion and normal subjects3 sessions of up to 4 h each
- Participants
- 6 vs 18
- Comparison
- Normal vs Patients with congestion
- Normaln = 6
- Patients with congestionn = 18
- Outcome
- Ability to increase skin temperature to the desired range (35 °C to 38 °C)
Main finding
As reported in the abstract
Skin temperature
- Skin temperature increased to median 37.5 °C (IQR 37.1-37.9 °C)
- Median core temperature increase 0.2 °C (IQR 0.1-0.3 °C)
Secondary outcomes
Hourly sweat output ≥150 mL/h
- Treatment procedures with average sweat rate ≥150 mL/h
- 80%
Hourly weight loss during treatment
- Median 215 g/h (IQR 165-285; range 100-344 g/h)
Safety
- No procedure-related adverse events
- No significant changes in hemodynamic variables or renal function
Original publication
Enhancing Sweat Rate Using a Novel Device for the Treatment of Congestion in Heart Failure. Circ Heart Fail. Published 2 November 2022. doi:10. 1161/ circheartfailure. 122. 009787
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