Acute cardiac care & resuscitation

Epidemic of the SARS-CoV-2 Omicron variant in Shanghai, China in 2022: Transient and persistent effects on Out-of-hospital cardiac arrests

ResuscitationPublished Retrospective cohort study

Authors' conclusion

The monthly number of OHCAs doubled during the Omicron epidemic in Shanghai, and it remained elevated for another two months. OHCA affected individuals with cardiovascular and cerebrovascular diseases more during and after the epidemic than before it.

Study context

Population
OHCA patients admitted to the Shanghai Emergency Medical Center, 2018–2022
Participants
55,104 OHCAs
Exposure
Omicron epidemic and post-epidemic periods vs pre-epidemic period
Outcome
Monthly number of OHCAs

Main finding

As reported in the abstract

Omicron epidemic

1702

events

Early post-epidemic

1515

events

Pre-epidemic

793

events

Omicron epidemic vs pre-epidemic
2.1 times
Early post-epidemic vs pre-epidemic
1.9 times

Observational data: associations, not effects.

Further findings

ROSC after OHCA

ROSC significantly lower during the epidemic than before it
aOR 0.61, 95% CI 0.41-0.90; P = 0.012
Difference disappeared by the early post-epidemic

Original publication

Epidemic of the SARS-CoV-2 Omicron variant in Shanghai, China in 2022: Transient and persistent effects on Out-of-hospital cardiac arrests. Resuscitation. Published 8 February 2023. doi:10.1016/j.resuscitation.2023.109722

Summarised from the published abstract; every number is checked against it

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