Valvular & structural heart diseaseCohort study
Evaluation of tricuspid valve regurgitation following transvenous rotational mechanical lead extraction
- Observational cohort study
Authors' conclusion
Significant TRI was detected in 5.7% of patients following transvenous rotational mechanical lead extraction. The duration of lead implantation emerged as the sole predictor of significant TRI.
Study context
- Population
- Patients undergoing mechanical rotational transvenous lead extraction (TLE)290 leads extracted
- Participants
- 158 patients
- Outcome
- Rate of significant acute tricuspid regurgitation increase (TRI: increase ≥1 grade with post-extraction severity at least moderate) by echocardiography
Main finding
As reported in the abstract
Significant TRI
Significant TRI
5.7%
Observational data: associations, not effects.
Further findings
Univariate predictors of significant TRI
| Comparison | OR (95% CI) | P value | |
|---|---|---|---|
| implant duration of all leads · univariate | 1.01 (1.003–1.018) | P = 0.001 | |
| right ventricular leads · univariate; implant duration | 1.01 (1.004–1.017) | P = 0.002 | |
| 0.512Odds ratio (log scale) |
Independent predictors of mortality
| Comparison | HR (95% CI) | P value | |
|---|---|---|---|
| Severe increase of TR following TLE · independent predictor | 5.20 (1.44–18.73) | P = 0.012 | |
| severe systolic dysfunction | 2.37 (1.01–5.20) | P = 0.032 | |
| systemic infection | 2.28 (1.06–4.89) | P = 0.035 | |
| 0.050.21520Hazard ratio (log scale) |
Original publication
Evaluation of tricuspid valve regurgitation following transvenous rotational mechanical lead extraction. Europace. Published 11 July 2024. doi:10.1093/europace/euae191
Summarised from the published abstract; every number is checked against it