Examining the relationship between anthropometric and body composition measures with coronary heart disease events: the multi-ethnic study of atherosclerosis
Authors' conclusion
Higher FM, waist-to-height ratio, and waist circumference were associated with increased risk for hard CHD events while higher FFM was associated with decreased risk.
Study context
- Population
- Men and women aged 45–85 years without clinically apparent CVD (Multi-Ethnic Study of Atherosclerosis (MESA) cohort)
- Participants
- 6,814 men
- Exposure
- Anthropometric and body composition measures and hard coronary heart disease (CHD) events
- Outcome
- Incident hard CHD events:
- Non-fatal myocardial infarction (MI)
- Resuscitated cardiac arrest
- CHD death
- Follow-up
- 10 years
Methodological detailspopulation-based, multi-ethnic, fat mass (FM) and fat free mass (FFM) estimated from bioelectrical impedance analysis at baseline (Exam 1)
- Population-based
- Multi-ethnic
- FM and FFM estimated from bioelectrical impedance analysis at baseline (Exam 1)
Main finding
As reported in the abstract
Hard CHD events, HR per SD unit increase
Hazard ratio (CI)P value
FM (per SD increase)
1.64(1.09–2.48)
P-value 0.019FFM (per SD increase)
0.24(0.08–0.76)
P-value 0.014Waist-to-height ratio (per SD increase)
1.21(1.08–1.35)
P-value 0.001Waist circumference (per SD increase)
1.14(1.03–1.28)
P-value 0.016BMInot significant
1.08(0.97–1.21)
P-value 0.158Each row per its own increment, as printed
Observational data: associations, not effects.
Original publication
Examining the relationship between anthropometric and body composition measures with coronary heart disease events: the multi-ethnic study of atherosclerosis. Eur J Prev Cardiol. Published 8 April 2025. doi:10.
Summarised from the published abstract; every number is checked against it