Prevention & lipidsCohort study
Examining the relationship between anthropometric and body composition measures with coronary heart disease events: the multi-ethnic study of atherosclerosis
- Prospective cohort study
- population-based
- multi-ethnic
Fat mass (FM) and fat free mass (FFM) estimated from bioelectrical impedance analysis at baseline (Exam 1)
Authors' conclusion
Higher FM, waist-to-height ratio, and waist circumference were associated with increased risk for hard CHD events while higher FFM was associated with decreased risk.
Study context
- Population
- Men and women aged 45–85 years without clinically apparent CVD (Multi-Ethnic Study of Atherosclerosis (MESA) cohort)
- Participants
- 6,814 men
- Exposure
- Anthropometric and body composition measures and hard coronary heart disease (CHD) events
- Outcome
- Incident hard CHD events:
- Non-fatal myocardial infarction (MI)
- Resuscitated cardiac arrest
- CHD death
- Follow-up
- 10 years
Main finding
As reported in the abstract
Hard CHD events, HR per SD unit increase
Hazard ratio (CI)P value
FM (per SD increase)
1.64(1.09–2.48)
P-value 0.019FFM (per SD increase)
0.24(0.08–0.76)
P-value 0.014Waist-to-height ratio (per SD increase)
1.21(1.08–1.35)
P-value 0.001Waist circumference (per SD increase)
1.14(1.03–1.28)
P-value 0.016BMInot significant
1.08(0.97–1.21)
P-value 0.158Each row per its own increment, as printed
Observational data: associations, not effects.
Original publication
Examining the relationship between anthropometric and body composition measures with coronary heart disease events: the multi-ethnic study of atherosclerosis. Eur J Prev Cardiol. Published 8 April 2025. doi:10.1093/eurjpc/zwaf212
Summarised from the published abstract; every number is checked against it