Arrhythmias & electrophysiologyResearch article
Excellent interobserver agreement and steep learning curve for target volume delineation for stereotactic arrhythmia radioablation using a commercial software
- Interobserver agreement study
Authors' conclusion
CardTV-EPinv creation showed excellent interobserver agreement and was faster and more robust using ADAS than 3D slicer.
Study context
- Population
- Patients considered for stereotactic arrhythmia radioablation (STAR) for ventricular tachycardia (VT)80 CardTV-EPinv created
- Participants
- 20 patients
- Comparison
- ADAS vs Slicer3D workflows; experienced operator vs 2nd-year medical student
- Outcome
- Interobserver variability, ease of use and learning curve for EAM-based target volume (CardTV-EPinv) creation and transfer
Main finding
As reported in the abstract
Interobserver agreement (Hausdorff distance) with ADAS, 20 patients
HD between observers
1.68 mm [1.45-1.96]
95th percentile HD
< 4.8 mm [3.5-5.7]
CardTV-EPinv size, operator vs student
11.8 mL [10.1-13.7] vs. 10.7 mL [9.6-11.8], P = 0.17
Steep learning curve for the student (linear regression)
P = 0.01
Further findings
Workflow duration
P < 0.001
events
| Outcome | ADAS | Slicer3D | P value |
|---|---|---|---|
| System crashes | 0 | 7 |
Agreement between ADAS and Slicer3D workflows
- HD
- 3.64 mm [2.7-4.5]
Original publication
Excellent interobserver agreement and steep learning curve for target volume delineation for stereotactic arrhythmia radioablation using a commercial software. Europace. Published 16 June 2025. doi:10.1093/europace/euaf122
Summarised from the published abstract; every number is checked against it