Heart failure & cardiomyopathiesResearch article
Excess Mortality and Hospitalizations Associated With Seasonal Influenza in Patients With Heart Failure
- Nationwide time-series study
- time series linear regression model
Authors' conclusion
Our results indicate that influenza activity likely causes substantial morbidity and mortality among patients with heart failure.
Study context
- Population
- Patients with HF in Denmark, 2010–2018 (8 influenza seasons)annual mean
- Participants
- 70,570 patients
- Outcome
- Annual excess number of deaths and hospitalizations associated with influenza infection
Main finding
As reported in the abstract
- Annual excess all-cause deaths
- 250 (95% CI 144-489)
- Share of all all-cause deaths
- 2.6% (95% CI 1.5%-5.1%)
- Annual excess CV deaths
- 115 (95% CI 62-244)
- Share of all CV deaths
- 2.9% (95% CI 1.5%-6.1%)
- Annual excess hospitalizations for pneumonia or influenza
- 251 (95% CI 107-533)
- Share of all hospitalizations for pneumonia or influenza
- 5.0%
Original publication
Excess Mortality and Hospitalizations Associated With Seasonal Influenza in Patients With Heart Failure. J Am Coll Cardiol. Published 31 August 2024. doi:10.1016/j.jacc.2024.08.048
Summarised from the published abstract; every number is checked against it