Heart failure & cardiomyopathiesMeta-analysis
Exercise-Based Cardiac Rehabilitation for Adults with Heart Failure – 2023 Cochrane Systematic Review and Meta-Analysis
- Systematic review and meta-analysis of randomised trials
- Cochrane review update
- stratified by delivery mode
Study context
- Population
- Adults with heart failure (HF) in RCTs with follow-up ≥6 months
- Participants
- 8,728 adults · 60 RCTs
- Comparison
- ExCR vs no-exercise control
Pooled result
As reported in the abstract
Mortality, hospitalization and HRQoL · short term (≤12 months)
ExCR vs ControlRelative risk (95% CI)
all-cause mortality
0.93(0.71–1.21)
all-cause hospitalization; NNT 13 (95% CI 9-22)
0.69(0.56–0.86)
ExCR vs ControlMean difference (95% CI)
MLWHF overall score (HRQoL)
−7.39(−10.30 to −4.47)
Further pooled results
All-cause mortality, all-cause hospitalization, MLWHF overall score (long term) · long-term follow-up (>12 months)
- Long-term mortality, RR
- 0.87 (95% CI 0.72-1.04)
- Long-term all-cause hospitalization, RR
- 0.84 (95% CI 0.70-1.01)
- Long-term MLWHF overall score
- −9.59 (95% CI −17.48 to −1.50)
- A similar pattern of results was seen in the long term
Outcomes by delivery mode
- Improvements with ExCR seen across centre, home (including digitally supported) and hybrid settings
Original publication
Exercise-Based Cardiac Rehabilitation for Adults with Heart Failure – 2023 Cochrane Systematic Review and Meta-Analysis. Eur J Heart Fail. Published 31 October 2023. doi:10.1002/ejhf.3046
Summarised from the published abstract; every number is checked against it