External validity of the PRECISE-DAPT score in patients undergoing percutaneous coronary intervention (PCI): a systematic review and meta-analysis
Pooled result · Any out-of-hospital bleedingResult — go to the resultOdds ratio 2.71 95% CI 2.24–3.29Authors' conclusion
This systematic review and meta-analysis confirms the external validity of the PRECISE-DAPT score in predicting out-of-hospital bleeding outcomes in patients on DAPT following PCI.
Study context
- Population
- Patients receiving DAPT after PCI
- Participants
- 67,283 patients21 studies
- Comparison
- High bleeding risk vs low bleeding risk
- High bleeding riskn = 16,603
- Outcome
- Any out-of-hospital bleeding
Methodological detailsrandom-effects model
- Random-effects model
Pooled result
As reported in the abstract
Odds ratio
2.71
95% CI 2.24–3.29
P < 0.001
High bleeding riskvs Low bleeding risk
OR 2.71 (95% CI 2.24–3.29); P < 0.001
Further pooled results
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Major bleeding | 3.51 (2.71–4.55) | P < 0.001 | |
| 0.20.5125Odds ratio (log scale) |
Discrimination of PRECISE-DAPT for major bleeding · 1 year
- Pooled c-stat (moderate discriminative power)
- 0.71 (95% CI: 0.64-0.77)
Original publication
External validity of the PRECISE-DAPT score in patients undergoing PCI: a systematic review and meta-analysis. Eur Heart J Cardiovasc Pharmacother. Published 26 August 2023. doi:10.
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