Feasibility of Simultaneous Quantification of Myocardial and Renal Perfusion With Cardiac Positron Emission Tomography
Authors' conclusion
Renal blood flow can be reliably measured from cardiac 13N-ammonia PET/CT and allows for simultaneous assessment of myocardial and renal perfusion
Study context
- Population
- Patients undergoing routine, clinically indicated 13N-ammonia myocardial perfusion positron emission tomography (PET)/computed tomography (CT)296 (76.7%) evaluable
- Participants
- 386 patients
- Outcome
- Feasibility of quantification of renal blood flow from cardiac 13N-ammonia PET/CT
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Evaluable images to quantify renal perfusion
296
76.7%
Reproducibility, intraclass correlation coefficient (3 readers)
0.98
95% CI 0.93–0.99
Correlation of renal blood flow with eGFR
r=0.64
P<0.001
Further findings
Resting renal blood flow vs stress myocardial blood flow and myocardial flow reserve
- Resting renal blood flow correlated with maximal stress myocardial blood flow and myocardial flow reserve
Resting renal blood flow vs histological interstitial fibrosis (kidney biopsy subgroup, n=12)
- Strong negative correlation
- r=−0.85; P<0.001
Original publication
Feasibility of Simultaneous Quantification of Myocardial and Renal Perfusion With Cardiac Positron Emission Tomography. Circ Cardiovasc Imaging. Published 1 September 2023. doi:10.
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