Arrhythmias & electrophysiologyCohort study
Five-year changes in alcohol intake and risk of atrial fibrillation: a Danish cohort study
- Prospective cohort study
- registry-linked
Authors' conclusion
A 5-year increase in alcohol intake was associated with a greater risk of AF compared with a stable low/moderate intake.
Study context
- Population
- Participants without prior atrial fibrillation (AF) in the Danish Diet, Cancer and Health cohort; median age 61 years, 54% female5,312 incident AF
- Participants
- 43,758 participants
- Exposure
- 5-year changes in alcohol intake vs stable intake
- Outcome
- Incident AF
- Follow-up
- Median 15.7 years
Main finding
As reported in the abstract
Each group vs stable intakeHazard ratio (95% CI)
≤6.9 to ≥21 drinks/week
1.38(1.09–1.72)
14-20.9 to ≥21 drinks/week
1.27(1.01–1.59)
- Overall AF incidence rate
- 8.6/1000 person-years
Observational data: associations, not effects.
Original publication
Five-year changes in alcohol intake and risk of atrial fibrillation: a Danish cohort study. Eur J Prev Cardiol. Published 12 December 2022. doi:10.1093/eurjpc/zwac293
Summarised from the published abstract; every number is checked against it