Heart failure & cardiomyopathiesRandomised controlled trial
Food Supplementation in Patients Hospitalized for Heart Failure
- Randomised controlled trial
- open-label
- factorial
- 2 hospitals
Authors' conclusion
In this randomized clinical trial, 90-day food supplementation was feasible and well accepted in individuals with recent HF. Food supplementation was not associated with an improvement in the primary clinical outcome and there was no difference when conditioning food supplementation on health care engagement.
Study context
- Population
- Patients hospitalized for heart failure (HF), enrolled within 14 days of discharge, 2 hospitals in Dallas, Texas
- Participants
- 150 patients
- Comparison
- Food supplementation vs usual care
- Food supplementationn = 100
- Usual caren = 50reference
- Primary endpoint
- Readmission for HF or emergency department (ED) visits for HF
- Follow-up
- 90-day follow-up
Primary result
HF readmission or ED visit · 90 days
Adjusted rate ratio
1.09
95% CI 0.49–2.43
P = 0.83
Events by treatment group
Food supplementation
23
events
Usual care
9
events
Food supplementation vs Usual care
adjusted rate ratio 1.09 (95% CI 0.49–2.43); P = 0.83
As reported in the abstract
Further findings
| Outcome | Values | win ratio (95% CI) | P value | |
|---|---|---|---|---|
| Hierarchical composite (all-cause death, total HF hospitalizations or ED visits, ≥10-point KCCQ-CSS improvement) | 1.21 (1.14–1.29) | P < 0.001 | ||
| 0.512Win ratio (log scale) |
| Outcome | Values | Estimate | P value |
|---|---|---|---|
| Acceptability (Net Promoter Score) | Fresh produce 8.6 · Medically tailored meals 7.3 | P = 0.02 | |
| Consumption adherence | Medically tailored meals mean 4.7 (SD 2.4) days per week · Fresh produce mean 5.5 (SD 2.3) days per week |
Feasibility
- Food delivery completion
- 93.6%
- Retention
- 96.0%
HF events, conditional vs unconditional delivery (food supplementation)
- Conditional delivery not associated with risk of HF events
Original publication
Food Supplementation in Patients Hospitalized for Heart Failure. JAMA Cardiol. Published 1 June 2026. doi:10.1001/jamacardio.2026.0435
Summarised from the published abstract; every number is checked against it