Valvular & structural heart diseaseCohort study
Frequency and Outcomes of Acute Hemodynamic Instability Following Transcatheter Tricuspid Valve Replacement
- Multicentre observational cohort study
- 5 international centres
Authors' conclusion
AHI is a life-threatening complication in the early postprocedural period following TTVR. Elevated left-sided filling pressures, pulmonary hypertension, and impaired renal function are associated with an increased risk for AHI
Study context
- Population
- Patients undergoing transcatheter tricuspid valve replacement (TTVR); mean age 78 ± 11 years, 64% women
- Participants
- 200 patients
- Exposure
- Acute hemodynamic instability (AHI) vs no AHI after TTVR
- Outcome
- Frequency of acute hemodynamic instability (AHI) after TTVR
Main finding
As reported in the abstract
Frequency of AHI
Frequency of AHI
8.5%
Observational data: associations, not effects.
Further findings
Intrahospital mortality
P < 0.001
Risk factors for AHI (univariate regression)
- Low GFR, reduced LVEF, decreased TAPSE/mean PA pressure ratio and elevated PCWP were significant factors of AHI
Original publication
Frequency and Outcomes of Acute Hemodynamic Instability Following Transcatheter Tricuspid Valve Replacement. JACC Cardiovasc Interv. Published 23 March 2026. doi:10.1016/j.jcin.2026.01.284
Summarised from the published abstract; every number is checked against it