Valvular & structural heart diseaseCohort study

From Theory to Practice

JACC AdvPublished

  • retrospective analysis

Authors' conclusion

GPT-based data extraction showed high accuracy across a broad range of variables, particularly continuous repeated measurements and rare intraoperative outcomes. Performance was lower for some infrequent postoperative events, reflecting sparse true positives. These findings support the feasibility of integrating LLM-assisted extraction into observational research workflows, with further validation needed in larger or multicenter cohorts.

Study context

Population
Patients undergoing transcatheter aortic valve replacement at Ca' Foncello Hospital (Treviso, Italy) between January and June 2024; medical and nursing records
Participants
108 cases
Exposure
GPT vs Manual abstraction

Further findings

Accuracy

valve brand
0.657
gender, Barthel index, procedure timings, and several intraoperative complications
1.00

Sensitivity

rare but clinically important events, including intraoperative neurological complications
1.00

Specificity

most variables
exceeded 0.90

Vital parameters (Bland-Altman)

minimal bias and narrow limits of agreement

Original publication

From Theory to Practice. JACC Adv. Published 11 June 2026. doi:10.1016/j.jacadv.2026.102871

Summarised from the published abstract; every number is checked against it