Heart failure & cardiomyopathiesDiagnostic or prognostic study

Fully Automatic AI-Based Quantification of Left Ventricular (LV) Mass in Echocardiography

JACC Cardiovasc ImagingPublished

  • Diagnostic accuracy study

Authors' conclusion

AI echocardiography provides superior accuracy, diagnostic performance, and reproducibility for LV mass assessment compared with expert evaluation

Study context

Population
Patients undergoing echocardiography and computed tomography (CT)bedside test-retest cohort n = 40
Participants
218 patients
Comparison
Artificial intelligence (AI) vs Expert
Outcome
Accuracy of echocardiographic LV mass vs CT (ICC, MAPE)

Performance

As reported in the abstract

Agreement with CT for LV mass
Test or modelIntraclass correlation coefficient (ICC), hybrid methodMean absolute percentage error (MAPE), hybrid methodICC, linear methodMAPE, linear method
AI0.760.160.490.44
AI vs Expert: reduction in measurement error, mainly due to more consistent interventricular septal diameter (IVSD) and posterior wall diameter (PWD) measurements
∼20%
RWT+ cases reclassified by AI vs Expert
34%

Further findings

OutcomeAIExpert
Diagnostic accuracy for increased LV mass (AUC)
AUC, linear0.780.71
AUC, hybrid0.840.77
Test-retest reliability (coefficient of variation), bedside cohort
CV, both mass methods7.8% and 8.1%Not reported in the abstract

Test-retest reliability (coefficient of variation), bedside cohort

Test-retest reliability highest with AI for both mass methods; reproducibility of manual assessment varied with operator skills

Original publication

Fully Automatic AI-Based Quantification of LV Mass in Echocardiography. JACC Cardiovasc Imaging. Published 29 October 2025. doi:10.1016/j.jcmg.2025.09.014

Summarised from the published abstract; every number is checked against it