Arrhythmias & electrophysiologyCohort study
General anaesthesia compared to conscious sedation for first-time atrial fibrillation catheter ablation—a Danish nationwide cohort study
- Nationwide cohort study
- Danish healthcare registries
- multivariable Cox proportional hazards analysis
Authors' conclusion
This nationwide cohort study suggests a higher risk of AF recurrence with CS during CA compared to GA.
Study context
- Population
- Adults (≥18 years) undergoing first-time catheter ablation for atrial fibrillation (AF) in Denmark, 2010–2018
- Participants
- 7,957 adults
- Exposure
- Conscious sedation (CS) vs general anaesthesia (GA)
- CSn = 6,421
- GAn = 1,536reference
- Outcome
- AF recurrence (composite:
- Antiarrhythmic drug prescriptions
- AF-related hospital admissions
- Electrical cardioversions
- AF re-ablation)
- Follow-up
- 5-year follow-up
Main finding
AF recurrence · 5 years
Hazard ratio
1.26
95% CI 1.15–1.38
By group
CS vs GA
HR 1.26 (95% CI 1.15–1.38)
As reported in the abstract
Observational data: associations, not effects.
Further findings
AF recurrence · 1 year · cumulative incidence
Original publication
General anaesthesia compared to conscious sedation for first-time atrial fibrillation catheter ablation—a Danish nationwide cohort study. Europace. Published 6 August 2024. doi:10.1093/europace/euae203
Summarised from the published abstract; every number is checked against it