Heart failure & cardiomyopathiesCohort study

General and disease-specific health literacy in patients with heart failure: an outcome analysis

ESC Heart FailPublished

  • prospective observational study

Authors' conclusion

In patients with HF, limited general health literacy was observed in 22% of patients. General and disease-specific health literacy measures were not interchangeable, and only disease-specific health literacy showed an independent association with self-care behaviours. A tendency towards less favourable clinical outcomes was observed among patients with limited general health literacy.

Study context

Population
Outpatients with heart failure (HF) followed for 6 monthsoutpatients with HF (mean age 69 ± 11 years, 71% male)
Participants
126 outpatients
Exposure
General and disease-specific health literacy and their association with behavioural, patient-reported and clinical outcomes

Main finding

As reported in the abstract

Correlation between the two measures

Spearman's ρ

0.49

P

P < .001

Observational data: associations, not effects.

Further findings

Limited general health literacy (Brief Health Literacy Screen (BHLS) ≤ 9)

Patients with limited general health literacy
22%
Associated with lower educational level, more depressive symptoms, higher NT-proBNP levels, and a greater number of prescribed medications
all P < .05

HF-related knowledge (univariable)

BHLS
P = 0.004
Heart Failure-Specific Health Literacy Scale (HFsHLS)
.049
  • not sustained after multivariable adjustment

Health-related quality of life (univariable)

BHLS
P < 0.001
HFsHLS
.007
  • not sustained after multivariable adjustment

Self-rated health (univariable)

Both measures
P < 0.001 for both
  • not sustained after multivariable adjustment

Self-care behaviours (disease-specific health literacy)

Univariable
P = 0.033
After multivariable adjustment
P = 0.026

Clinical outcomes (death, HF hospitalization, emergency department visit)

Neither measure was independently associated with clinical outcomes
Patients with limited general health literacy showed numerically higher event rates and a tendency towards increased risk of clinical outcomes

Original publication

General and disease-specific health literacy in patients with heart failure: an outcome analysis. ESC Heart Fail. Published 23 July 2026. doi:10.1093/eschf/xvag204

Summarised from the published abstract; every number is checked against it