Acute cardiac care & resuscitation
Global myocardial oedema in resuscitated out-of-hospital cardiac arrest patients assessed by cardiac magnetic resonance: a pilot study
Authors' conclusion
Assessed with CMR, we for the first time document an early global myocardial oedema in patients successfully resuscitated from OHCA.
Study context
- Population
- Comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA) admitted to the cardiac ICU
- Comparison
- Resuscitated OHCA patients vs healthy controls
- OHCAn = 16
- Controlsn = ninereference
- Outcome
- Global myocardial oedema (mean global T1 and T2 time on CMR)
- Follow-up
- Within 36 h after cardiac arrest
Methodological detailsconsecutive inclusion, healthy controls
- Consecutive inclusion
- Healthy controls
Main finding
As reported in the abstract
| Group | T1 | T2 |
|---|---|---|
| OHCA | 1071 ms | 52 ms |
| Controls | 999 ms | 46 ms |
T1
OHCA1071 ms
Controls999 ms
T2
OHCA52 ms
Controls46 ms
- OHCA vs Controls: P = 0.002 — T1
- OHCA vs Controls: P < 0.001 — T2
Observational data: associations, not effects.
Further findings
LVEF by transthoracic echocardiography (OHCA patients) · admission vs during hospitalization
- LVEF on admission
- 35 ± 15%
- LVEF during hospitalization (significant improvement)
- 43 ± 14%
- P < 0.05
Original publication
Global myocardial oedema in resuscitated out-of-hospital cardiac arrest patients assessed by cardiac magnetic resonance: a pilot study. Eur Heart J Acute Cardiovasc Care. Published 26 December 2022. doi:10.
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