Arrhythmias & electrophysiology
Global, regional, and national burden of atrial fibrillation/flutter related to metabolic risks over three decades: estimates from the global burden of disease study 2019
Authors' conclusion
The global AF/AFL burden related to metabolic risks has significantly increased over the past three decades, with considerable spatiotemporal, gender-based, and age-related heterogeneity.
Study context
- Population
- Global population, metabolic risk-related AF/atrial flutter burden, 1990–2019, by age, sex, sociodemographic index (SDI) and location
- Primary endpoint
- Numbers and age-standardized rates of deaths and DALYs, and estimated annual percentage change
Primary result
As reported in the abstract
Metabolic risk-related AF/AFL burden worldwide · 2019
Deaths in 2019
137 179
Disability-adjusted life years (DALYs) in 2019
4 099 146
Increase in deaths from 1990
162.95%
Increase in DALYs from 1990
120.30%
Further findings
Burden by SDI
- Burden predominantly in high and high-middle SDI regions, with a shift towards lower SDI regions
- Asymmetrically inverted V-shaped correlation between SDI and deaths/DALYs rates
Highest national rates (Montenegro)
Per 100 000
- Death rate
- 7.6
- DALYs rate
- 146.3
Burden by sex and age
- Higher burden in females and the elderly; annual increase in young adults (over 40 years old)
Original publication
Global, regional, and national burden of atrial fibrillation/flutter related to metabolic risks over three decades: estimates from the global burden of disease study 2019. Eur Heart J Qual Care Clin Outcomes. Published 6 May 2024. doi:10.
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