Coronary disease & ACS

Great debate: the new risk factor–weighted clinical likelihood model is useful to estimate the initial pre-test probability of obstructive coronary artery disease in individuals with suspected chronic coronary syndromes

Eur Heart JPublished Great Debate

An erratum to this article was published (Eur Heart J, 9 Jun 2026 ↗)

Authors' conclusion

The RF-CL model undoubtedly improves the prediction of obstructive CAD and can 'de-risk' a significant number of symptomatic patients safely, reducing unnecessary testing.

Study context

Population
Individuals with suspected chronic coronary syndrome
Outcome
Usefulness of the 2024 ESC RF-CL model for pre-test probability of obstructive coronary artery disease (CAD)
Methodological detailsexpert opinion
  • Expert opinion

Main finding

As reported in the abstract

Very high likelihood (estimated score >85%): invasive coronary angiography recommended; how this score is reached not entirely clear

> 85%

Original publication

Great debate: the new risk factor–weighted clinical likelihood model is useful to estimate the initial pre-test probability of obstructive coronary artery disease in individuals with suspected chronic coronary syndromes. Eur Heart J. Published 13 March 2026. doi:10.1093/eurheartj/ehag091

Composed by AI from the published abstract and checked against it. How Briefs are made →

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