Coronary disease & ACSResearch article
Great debate: the new risk factor–weighted clinical likelihood model is useful to estimate the initial pre-test probability of obstructive coronary artery disease in individuals with suspected chronic coronary syndromes
- Great Debate (expert opinion)
Authors' conclusion
The RF-CL model undoubtedly improves the prediction of obstructive CAD and can 'de-risk' a significant number of symptomatic patients safely, reducing unnecessary testing.
Study context
- Population
- Individuals with suspected chronic coronary syndrome
Main finding
As reported in the abstract
Usefulness of the 2024 ESC RF-CL model for pre-test probability of obstructive coronary artery disease (CAD)
Very high likelihood (estimated score >85%): invasive coronary angiography recommended; how this score is reached not entirely clear
> 85%
Original publication
Great debate: the new risk factor–weighted clinical likelihood model is useful to estimate the initial pre-test probability of obstructive coronary artery disease in individuals with suspected chronic coronary syndromes. Eur Heart J. Published 13 March 2026. doi:10.1093/eurheartj/ehag091
Summarised from the published abstract; every number is checked against it