Heart failure & cardiomyopathiesCohort study

Health Care Use and Outcomes in Heart Failure

JACC AdvPublished

  • Retrospective cohort study using interrupted time series (ITS)
  • adjusted for age, sex, socioeconomic status, comorbidity burden, seasonality, and pre-pandemic trends

Authors' conclusion

The declines in hospitalizations and ED visits seen during the pandemic continued post-pandemic, severity of presentation increased, and the decline in non-COVID mortality rates was consistent with pre-pandemic trends.

Study context

Population
Patients with heart failure (HF), March 2018 to May 2024patients per period · pre-pandemic 66,782 · intra-pandemic 77,473 · post-pandemic 82,072
Participants
66,782 / 77,473 / 82,072
Exposure
monthly rates of mortality, hospitalizations, emergency department (ED) visits, and ambulatory care visits in patients with HF pre-pandemic, intra-pandemic, and post-pandemic
  • pre-pandemicn = 66,782reference
  • intra-pandemicn = 77,473
  • post-pandemicn = 82,072

Main finding

As reported in the abstract

Canadian Triage Acuity Scores in patients with HF presenting to an ED or being hospitalized

More severe Canadian Triage Acuity Scores during and post-pandemic than pre-pandemic (both P < 0.001)

P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeIncidence rate ratio
All-cause hospitalizations (monthly) · median follow-up 2.9 years (IQR: 1.1-5.9 years) — intra-pandemic vs pre-pandemic · lower during pandemic · adjusted for covariates and pre-pandemic trends0.83 (95% CI 0.81–0.86)
All-cause hospitalizations (monthly) · median follow-up 2.9 years (IQR: 1.1-5.9 years) — post-pandemic vs pre-pandemic · lower post-pandemic · adjusted for covariates and pre-pandemic trends0.81 (95% CI 0.78–0.84)
All-cause ED visits (monthly) · median follow-up 2.9 years (IQR: 1.1-5.9 years) — intra-pandemic vs pre-pandemic · lower during pandemic · adjusted for covariates and pre-pandemic trends0.81 (95% CI 0.78–0.84)
All-cause ED visits (monthly) · median follow-up 2.9 years (IQR: 1.1-5.9 years) — post-pandemic vs pre-pandemic · lower post-pandemic · adjusted for covariates and pre-pandemic trends0.84 (95% CI 0.80–0.89)
Non-COVID mortality rates · lower post-pandemic0.58 (CI 0.53–0.63)
  • All-cause hospitalizations (monthly): ITS P = 0.001
  • All-cause ED visits (monthly): ITS P = 0.005
  • Non-COVID mortality rates: ITS analysis: not a significant departure from pre-pandemic trends (P = 0.79)

Original publication

Health Care Use and Outcomes in Heart Failure. JACC Adv. Published 10 July 2026. doi:10.1016/j.jacadv.2026.102986

Summarised from the published abstract; every number is checked against it