Heart failure & cardiomyopathiesCross-sectional study

Health Status in Heart Failure and Cancer

JACC Heart FailPublished

  • Cross-sectional study
  • pooled analysis of Medicare Health Outcomes Survey data 2016–2020

Authors' conclusion

People with HF experience worse HRQOL than those with cancer actively receiving treatment.

Study context

Population
Medicare participants ≥65 years of age with heart failure (HF) or actively treated cancer
Participants
71,025 / 4,165 / 4,270 / 14,542 / 17,670
Exposure
HF vs lung, colorectal, breast and prostate cancer
  • HFn = 71,025reference
  • Lungn = 4,165
  • Colorectaln = 4,270
  • Breastn = 14,542
  • Prostaten = 17,670
Outcome
Health-related quality of life (HRQOL): Veterans RAND-12 physical component score (PCS) and mental component score (MCS) (0-100, population mean 50, SD 10)

Main finding

As reported in the abstract

Mean PCS and MCS
GroupPhysical component score (PCS)Mental component score (MCS)
HF29.547.9
Lung31.231.2
Colorectal35.650.0
Breast37.752.0
Prostate39.653.0
Mean PCS lower in HF than in each cancer (all comparisons)
P < 0.001
Mean MCS significantly lower in HF than in each cancer (all comparisons)
P < 0.001

Observational data: associations, not effects.

Original publication

Health Status in Heart Failure and Cancer. JACC Heart Fail. Published 6 November 2023. doi:10.1016/j.jchf.2023.10.003

Summarised from the published abstract; every number is checked against it