Heart failure & cardiomyopathies

Healthcare utilization and left ventricular ejection fraction distribution in methamphetamine use associated heart failure hospitalizations

Am Heart JPublished Retrospective cohort study

Authors' conclusion

While the majority of MU-HF hospitalizations are HFrEF, a sizeable minority have HFpEF.

Study context

Population
Veterans with a first HF hospitalization in Veterans Affairs (VA) medical centers, 2007–2020
Participants
203,005 first-time HF hospitalizations
Exposure
Methamphetamine use associated HF vs HF not associated with methamphetamine use
  • MU-HFn = 4,080
Outcome
LVEF distribution, methamphetamine use treatment engagement and postdischarge healthcare utilization
Methodological detailsVA Corporate Data Warehouse, left ventricular ejection fraction (LVEF) identified with a validated natural language processing algorithm
  • VA Corporate Data Warehouse
  • LVEF identified with a validated natural language processing algorithm

Main finding

As reported in the abstract

LVEF
GroupValueLVEF ≥ 50%
MU-HFMedian 30 (IQR 20–45) %Eighteen percent
other-HFMedian 40 (IQR 25–55) %28%

Value

MU-HFMedian 30 (IQR 20–45) %
other-HFMedian 40 (IQR 25–55) %

LVEF ≥ 50%

MU-HFEighteen percent
other-HF28%
  • MU-HF vs other-HF: P < 0.0001 — median LVEF

Observational data: associations, not effects.

Further findings

Discharge against medical advice

Post-discharge ED visits and rehospitalizations · 30 days

ED visits

Rehospitalizations

Methamphetamine use treatment engagement and primary care follow-up (MU-HF) · 30 days post discharge
18% · Methamphetamine use treatment engagement · Primary care follow-up 76%

Original publication

Healthcare utilization and left ventricular ejection fraction distribution in methamphetamine use associated heart failure hospitalizations. Am Heart J. Published 11 March 2024. doi:10.1016/j.ahj.2023.12.014

Composed by AI from the published abstract and checked against it. How Briefs are made →

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