Healthy Dietary Patterns and Incident Cardiovascular Disease in Cancer Survivors: A Prospective Cohort Study
Authors' conclusion
Adherence to healthy dietary patterns is associated with reduced CVD risk among cancer survivors, underscoring the potential for diet to support cardio-oncology care.
Study context
- Population
- Cancer survivors initially free of cardiovascular disease (CVD) in the UK Biobank cohortcancer survivors initially free of CVD
- Participants
- 8,716 survivors
- Exposure
- Comparing the top quintile with the bottom quintile
- Outcome
- Incident CVD events
- Follow-up
- Median 12.3 (Q1-Q3: 11.6-13.0) years
Methodological details24-hour dietary recall data, Cox proportional hazards models, Fine-Gray competing risks models
- 24-hour dietary recall data
- Cox proportional hazards models
- Fine-Gray competing risks models
Main finding
As reported in the abstract
- Individuals who experienced incident CVD events
- 1,116
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Total CVD · median follow-up of 12.3 (Q1-Q3: 11.6-13.0) yearsTop quintile vs bottom quintile · Mediterranean diet score | 0.72 (0.58–0.88) | |
| Total CVD · median follow-up of 12.3 (Q1-Q3: 11.6-13.0) yearsTop quintile vs bottom quintile | 0.74 (0.61–0.89) | |
| Total CVD · median follow-up of 12.3 (Q1-Q3: 11.6-13.0) yearsTop quintile vs bottom quintile · Alternate Healthy Eating Index-2010 | 0.63 (0.52–0.76) | |
| Total CVD · median follow-up of 12.3 (Q1-Q3: 11.6-13.0) yearsTop quintile vs bottom quintile · Dietary Approaches to Stop Hypertension score | 0.65 (0.53–0.79) | |
| Total CVD · median follow-up of 12.3 (Q1-Q3: 11.6-13.0) yearsTop quintile vs bottom quintile · healthful Plant-Based Diet Index | 0.82 (0.68–0.99) | |
| Total CVD · median follow-up of 12.3 (Q1-Q3: 11.6-13.0) yearsTop quintile vs bottom quintile · reversed energy-adjusted diet inflammatory index | 0.67 (0.55–0.80) | |
| Total CVD · median follow-up of 12.3 (Q1-Q3: 11.6-13.0) yearsTop quintile vs bottom quintile · healthy low-fat diet score | 0.80 (0.67–0.96) | |
| 0.512Hazard ratio (log scale) |
- Total CVD: Mediterranean-Dietary Approaches to stop Hypertension Diet Intervention for Neurodegenerative Delay score
- Total CVD: The findings remain robust after fitting the generalized propensity score model.
Estimated life expectancy at age 45
- Life expectancy gained, highest vs lowest adherence to healthy dietary patterns
- 1.66 to 3.32 years
Original publication
Healthy Dietary Patterns and Incident Cardiovascular Disease in Cancer Survivors: A Prospective Cohort Study. JACC Adv. Published 29 October 2026. doi:10.
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