Heart failure & cardiomyopathiesDiagnostic or prognostic study
Heart failure risk stratification at the time of implantable cardioverter-defibrillator implantation after myocardial infarction: The heart failure (HF) WICD-MI score
- development of a simple score
- 41 French centers
- external validation
Authors' conclusion
In patients undergoing post-MI ICD implantation, a simple HF-based score identifies patients at a higher risk of early postimplant HF events and may support integrated management, including timely HF referral.
Study context
- Population
- Patients with left ventricular ejection fraction of ≤35% after acute myocardial infarction (AMI) who were equipped with a wearable cardioverter-defibrillator (WCD) and were subsequently implanted with an implantable cardioverter-defibrillator (ICD)patients from the WICD-MI study, external validation n = 22,418 · WICD-MI study 1,015 · External validation in high-risk myocardial infarction 22,418
- Participants
- 1,015 patients
- Comparison
- HF WICD-MI score vs Global Registry of Acute Coronary Events and VALIANT-HF for HF hospitalization (external validation)
- Outcome
- Composite of:
- Death
- HF events (hospitalization, left ventricular (LV) assist device, or transplantation)
- Follow-up
- 1 year post-ICD
Performance
As reported in the abstract
- 1-year risk of the composite outcome
- 12.7%
- Cardiogenic shock, aHR
- 1.63, P = .013
- Congestive HF, aHR
- 2.02, P = .0004
- Acute HF hospitalization, aHR
- 2.96, P < .0001
- New York Heart Association III/IV, aHR
- 1.64, P = .025
Further findings
| Outcome | ΔC-index | P value |
|---|---|---|
| Discrimination for HF hospitalization, external validation · improved discrimination | +0.026 | P = 0.001 |
Risk by score points/HF features
- No points/HF features
- 5%
- ≥3 points/HF features
- 38%
Discrimination for HF hospitalization, external validation
- Performance similar to that of VALIANT-HF, with greater simplicity
Original publication
Heart failure risk stratification at the time of implantable cardioverter-defibrillator implantation after myocardial infarction: The HF WICD-MI score. Heart Rhythm. Published 14 August 2026. doi:10.1016/j.hrthm.2026.08.011
Summarised from the published abstract; every number is checked against it