Heart failure & cardiomyopathies
Heart failure with preserved ejection fraction management: a systematic review of clinical practice guidelines and recommendations
Authors' conclusion
There were discrepancies in recommended frequency of surveillance for patients with HFpEF and sparse recommendations on screening for HFpEF in the general population, use of diagnostic scoring systems, and the role of newly emerging therapies.
Study context
- Population
- Adults with heart failure with preserved ejection fraction (HFpEF); national and international guidelines and recommendations on management, published over the last 10 years7 retained for analysis
- Participants
- 10 adults
Methodological detailsMEDLINE and EMBASE searched on 28 February 2024, plus websites of organizations relevant to guideline development
- MEDLINE and EMBASE searched on 28 February 2024, plus websites of organizations relevant to guideline development
Pooled result
As reported in the abstract
- Consensus on the definition of HFpEF and the diagnostic role of serum natriuretic peptides and resting transthoracic echocardiography
- Discrepancies in the serum natriuretic peptide and transthoracic echocardiography thresholds used to diagnose HFpEF
- Agreement on general pharmacological and supportive management of acute and chronic HFpEF; differences in strategies to identify and address specific phenotypes
- Agreement on measures to avoid HFpEF development and on considering cardiac transplantation in advanced disease
- Discrepancies in the recommended frequency of surveillance; sparse recommendations on screening of the general population, diagnostic scoring systems and newly emerging therapies
Original publication
Heart failure with preserved ejection fraction management: a systematic review of clinical practice guidelines and recommendations. Eur Heart J Qual Care Clin Outcomes. Published 25 June 2024. doi:10.
Summarised from the published abstract; every number is checked against it