High-sensitivity C-reactive protein and cardiovascular events in a multi-ethnic cohort: the HEalthy Life In an Urban Setting (HELIUS) study
Authors' conclusion
hsCRP was associated with incident cardiovascular events in individuals of European and African descent but not in South Asian individuals, despite higher hsCRP values.
Study context
- Population
- General population, multi-ethnic HELIUS cohort (Dutch, South-Asian Surinamese, African Surinamese, Ghanaian, Turkish and Moroccan origin); mean age 44±13 years, 55% female568 CV events
- Participants
- 14,663 participants
- Exposure
- High-sensitivity C-reactive protein (hsCRP) and CV events across ethnic groups
- Outcome
- CV events (from nationwide registries) by hsCRP
- Follow-up
- Median 8.8 (7.8-9.7) years
Methodological detailsgeneral population, multi-ethnic
- General population
- Multi-ethnic
Main finding
As reported in the abstract
CV events per 1 mg/L increase in hsCRP
Adjusted HR per 1 mg/L hsCRP (95% CI)
European
1.08(1.00–1.16)
African
1.09(1.03–1.16)
Per 1 mg/L increase in hsCRP, as printed
Observational data: associations, not effects.
Further findings
Baseline hsCRP
- Baseline hsCRP — Difference across groups
- p <0.001
Original publication
High-sensitivity C-reactive protein and cardiovascular events in a multi-ethnic cohort: the HELIUS study. Eur J Prev Cardiol. Published 19 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →