Hemodynamic, ventilatory and gas exchange responses to exercise using a cycle ergometer and the incremental shuttle walk test in pregnant women
Authors' conclusion
CPET and ISWT are safe and feasible in women in second trimester including those at or beyond 24 weeks gestation.
Study context
- Population
- Healthy pregnant women in second trimester (14 to 27 gestational weeks)28 also completed incremental shuttle walk test (ISWT)
- Participants
- 90 women
- Outcome
- Reference intervals for V̇O2 at rest, anaerobic threshold (AT) and submaximal exercise by CPET, and for ISWT distance
Methodological detailssingle-centre, tertiary referral hospital, Mean ± SD age 32 ± 3.2 years; Body mass index (BMI) 25 ± 2.7 kg/m²; median (IQR) gestation 23 (22-24) weeks
- Single-centre
- Tertiary referral hospital
- Mean ± SD age 32 ± 3.2 years; BMI 25 ± 2.7 kg/m²; median (IQR) gestation 23 (22-24) weeks
Main finding
As reported in the abstract
Reference intervals in second trimester
- V̇O2 at rest (cardiopulmonary exercise testing (CPET)), mL/kg/min
- 2.9 to 5.3
- V̇O2 at anaerobic threshold (AT) (CPET), mL/kg/min
- 8.1 to 20.7
- Submaximal V̇O2 (CPET), mL/kg/min
- 14.1 to 30.5
- ISWT distance, meters
- 218 to 1058
- Equation predicting submaximal V̇O2 from ISWT distance
- submaximal V̇O2 (mL/kg/min) = 0.012*distance walked in ISWT (m) + 14.7
- Pearson r, ISWT distance vs submaximal V̇O2
- 0.5426 95%CI 0.2126-0.7615, P = .0029
Observational data: associations, not effects.
Further findings
Prediction of submaximal V̇O2 from ISWT distance
- Submaximal V̇O2 (mL/kg/min) = 0.012*ISWT distance (m) + 14.7; 95% CI slope 0.005-0.070
- Pearson r = 0.5426 (95%CI 0.2126-0.7615), P = .0029
Hemoglobin (Hb) vs V̇O2 at AT
- Positive correlation: AT V̇O2 (mL/kg/min) = 0.08*Hb (g/L) + 4.9; 95% CI slope 0.0791-0.143
- Pearson r = 0.2538 (95%CI 0.049-0.438), P = .016
Ferritin vs submaximal V̇O2
- No linear association
- Pearson r = 0.431, P = .697
Safety
- No maternal or fetal complications
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Hemodynamic, ventilatory and gas exchange responses to exercise using a cycle ergometer and the incremental shuttle walk test in pregnant women. Am Heart J. Published 15 March 2024. doi:10.
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