Prevention & lipidsCross-sectional study
Heterogeneity of Apolipoprotein B Levels Among Hispanic or Latino Individuals Residing in the US
- Cross-sectional study
- population-based
- sampling weights
- 4 US metropolitan areas
Authors' conclusion
In this cohort study among participants from the HCHS/SOL, elevated apoB was present in one-quarter of a diverse cohort study of Hispanic or Latino individuals who were at intermediate or high predicted ASCVD risk.
Study context
- Population
- Hispanic or Latino adults aged 18 to 74 years in 4 US metropolitan areas (HCHS/SOL), screened 2008–20118,376 (51.9%) female
- Outcome
- ApoB tertiles; traditional lipids across apoB tertiles; apoB and traditional lipids across ASCVD risk categories
Main finding
As reported in the abstract
Overall mean (SD) Apolipoprotein B (apoB)
99.8 (0.4) mg/dL
Mean apoB, male vs female participants (significantly higher in male)
102.4 vs 97.4 mg/dL
Mean apoB across Hispanic or Latino backgrounds (significant heterogeneity), Dominican to Cuban
95.1 mg/dL to 104.8 mg/dL
Observational data: associations, not effects.
Further findings
Elevated apoB (≥130 mg/dL) by predicted atherosclerotic cardiovascular disease (ASCVD) risk
- Elevated apoB with 10-year predicted ASCVD risk ≥7.5%
- 26.5%
- Prevalence greater across higher predicted ASCVD risk categories
Continental genetic ancestry by apoB tertile
- Median West African ancestry lower across higher apoB tertiles
Original publication
Summarised from the published abstract; every number is checked against it