Cardiometabolic & kidneyMeta-analysis
Higher risk of adverse cardiovascular outcomes in females with type 2 diabetes Mellitus: an Umbrella review of systematic reviews
- Umbrella review of systematic reviews and meta-analyses
Authors' conclusion
This umbrella review demonstrates that females with T2DM have a higher risk of cardiovascular outcomes than their male counterparts.
Study context
- Population
- Patients with T2DM27 reviews
- Comparison
- Females vs males with T2DM
Pooled result
As reported in the abstract
CV outcomes
- Coronary heart disease (CHD)
- RRR 1.52 (95% CI 1.32–1.76); P < 0.001
- Acute coronary syndrome (ACS)
- RRR 1.38 (95% CI 1.25–1.52); P < 0.001
- HF
- RRR 1.09 (95% CI 1.05–1.13); P < 0.001
- all-cause mortality
- RRR 1.13 (95% CI 1.07–1.19); P < 0.001
- cardiac mortality
- RRR 1.49 (95% CI 1.11–2.00); P = 0.009
- CHD mortality
- RRR 1.44 (95% CI 1.20–1.73); P < 0.001
Original publication
Higher risk of adverse cardiovascular outcomes in females with type 2 diabetes Mellitus: an Umbrella review of systematic reviews. Eur J Prev Cardiol. Published 26 April 2023. doi:10.1093/eurjpc/zwad133
Summarised from the published abstract; every number is checked against it