Cardio-oncology & otherCohort study
Hospitalization for cardiovascular disease in the year after delivery of twin pregnancies
- Retrospective cohort study
- nationwide database
Authors' conclusion
Compared with singletons without HDP, twin pregnancies, even in the absence of HDP, are associated with increased risks for CVD complications in the first year post-partum.
Study context
- Population
- Delivery hospitalizations, US Nationwide Readmissions Database, 2010–2020
- Participants
- 36 million delivery hospitalizations
- Exposure
- Twin vs singleton deliveries, with and without hypertensive disease of pregnancy (HDP)
- Outcome
- CVD readmission
- Follow-up
- Within the year following delivery
Main finding
As reported in the abstract
first year post-partum
Each group vs singletons without HDPAdjusted hazard ratio (95% CI)
Twins with HDP
8.21(7.48–9.01)
Singletons with HDP
5.89(5.70–6.08)
Twins without HDP
1.95(1.75–2.17)
- Cardiovascular disease (CVD) readmission rate, twin pregnancies
- 1105.4 per 100 000 delivery admissions
- CVD readmission rate, singleton pregnancies
- 734.1 per 100 000 delivery admissions
Observational data: associations, not effects.
Original publication
Hospitalization for cardiovascular disease in the year after delivery of twin pregnancies. Eur Heart J. Published 3 February 2025. doi:10.1093/eurheartj/ehaf003
Summarised from the published abstract; every number is checked against it